Qushi Huayu Decoction Inhibits Hepatic Lipid Accumulation by Activating AMP-Activated Protein Kinase In Vivo and In Vitro

Figure 2

Effect of QHD on hepatic morphology and pathological changes. (A) The liver samples of ND, HDF, and HFD + QHD rats. (B) Histological micrograph of liver specimen from ND, HDF, and HFD + QHD rats (H&E and oil red O staining, magnification ×200). (a) The ND group; (b) the HFD group; (c) the HFD + QHD group. The major histopathological change induced by HFD in rat liver was hepatocyte steatosis (filled arrow) with inflammation (arrowhead) and ballooning (open arrow).