Research Article

Qushi Huayu Decoction Inhibits Hepatic Lipid Accumulation by Activating AMP-Activated Protein Kinase In Vivo and In Vitro

Table 2

Body weight, food intake, and biochemical parameters in rats in different study groups.

ParameterND ( )HFD ( HFD + QHD ( )

Body weight before treatment (g)168.7 ± 6.9170.2 ± 5.4171.1 ± 6.3
Body weight after treatment (g)375.3 ± 19.9411.9 ± 33.4**392.6 ± 32.9
Food intake (g rat−1 per day)19.8 ± 2.322.1 ± 2.521.6 ± 2.1
Liver
 TG (mg/g)11.4 ± 6.454.7 ± 20.3**29.2 ± 11.7##
 FFA (μmol/g prot)475 ± 178786 ± 174**518 ± 139#
Serum
 TG (mmol/L)0.23 ± 0.060.31 ± 0.09**0.26 ± 0.05
 FFA (mmol/L)0.53 ± 0.100.63 ± 0.09*0.62 ± 0.07
 HDL-C (mmol/L)0.41 ± 0.050.34 ± 0.07**0.37 ± 0.09
 LDL-C (mmol/L) 0.65 ± 0.181.11 ± 0.27**0.85 ± 0.10##
 ALT (U/L)31.8 ± 6.567.9 ± 16.2**44.3 ± 15#
 AST (U/L)80.7 ± 15.8135.4 ± 15**52.1 ± 21.4##

Quantitative data are expressed as mean ± SD. Statistical analysis of the data for multiple comparisons was performed by ANOVA.
, versus the ND group.
, versus the ND group.
, versus the HFD group.
, versus the HFD group.