Yueju Pill Rapidly Induces Antidepressant-Like Effects and Acutely Enhances BDNF Expression in Mouse Brain

Figure 5

eEF2 phosphorylation at 30 minutes and 24 hours after an acute administration of Yueju. (a) Densitometric analysis of phosphorylated eEF2 (p-eEF2) normalized to total eEF2 in mouse hippocampus at 30 minutes after treatment with Yueju (YJ) or ketamine (KET). ANOVA, 𝐹_(2,15)=10.95; 𝑃=0.010. (b) Densitometric analysis of p-eEF2 normalized to total eEF2 in mouse hippocampus at 24 hours after drug treatment. ANOVA, 𝐹_(2,15)=31.34; 𝑃=0.001. *𝑃<0.05; ***𝑃<0.001, compared with the control group (CTL). Data represent mean ± SEM. 𝑛=6.

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