Synergistic Anticancer Effects of Vorinostat and Epigallocatechin-3-Gallate against HuCC-T1 Human Cholangiocarcinoma Cells
Figure 4
The combined effect of vorinostat and EGCG was assessed on angiogenic activity of tumor cells. HUVECs were used for the angiogenesis assay. Treated media from tumor cell cultured with the combination of vorinostat and EGCG were added to HUVECs. (a) The length of tubes and the numbers of junction were counted and compared with those of the control. (b) Western blot assay: VEGF expression and ratio. *P < 0.05; **P < 0.01; ***P < 0.001.
