Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Tab 5

Research Article

Beta-Glucan-Rich Extract from Pleurotus sajor-caju (Fr.) Singer Prevents Obesity and Oxidative Stress in C57BL/6J Mice Fed on a High-Fat Diet

Table 5

Effects of GE on enzymic antioxidants and MDA levels in the kidney and liver homogenates of C5BL/6J mice fed on a high-fat diet.

GroupsAntioxidant activity (nmol/min/mg protein)
GPxCATSOD (U/mg protein)LPO (mmol/L)

ND
Kidney 
Liver
71.08 ± 6.3cd
83.95 ± 10.8b
103.93 ± 4.5d
29.96 ± 3.9c
0.34 ± 0.0d
0.17 ± 0.0b
0.89 ± 0.01e
0.76 ± 0.03b

ND240Kidney 
Liver
82.72 ± 6.9d
90.42 ± 11.7b
112.96 ± 4.6e
32.57 ± 6.7d
0.37 ± 0.0d
0.32 ± 0.0d
0.83 ± 0.04d
0.7 ± 0.1ab

HFDKidney 
Liver
32.31 ± 3.2a
45.22 ± 5.5a
52.64 ± 1.2a
15.18 ± 8.7a
0.017 ± 0.0a
0.01 ± 0.0a
0.9 ± 0.04e
0.92 ± 0.1c

HFD60Kidney 
Liver
32.46 ± 4.9a
68.20 ± 8.3b
79.72 ± 1.3b
22.98 ± 5.7b
0.23 ± 0.0b
0.19 ± 0.0b
0.86 ± 0.02de
0.62 ± 0.1a

HFD120Kidney 
Liver
36.16 ± 5.1ab
74.86 ± 8.7b
86.40 ± 11.6bc
24.91 ± 9.7bc
0.27 ± 0.0c
0.23 ± 0.0bc
0.64 ± 0.03b
0.6 ± 0.04a

HFD240Kidney 
Liver
44.58 ± 5.3b
61.39 ± 8.9b
84.29 ± 1.5bc
24.30 ± 1.1bc
0.22 ± 0.0b
0.26 ± 0.0c
0.57 ± 0.04a
0.61 ± 0.06a

HFDMETKidney 
Liver
66.83 ± 5.5c
119.06 ± 9.3c
89.49 ± 2.7c
25.80 ± 8.5bc
0.20 ± 0.0b
0.19 ± 0.0b
0.74 ± 0.03c
0.64 ± 0.05ab

GE concentrations were 60, 120, and 240 mg/kg/day. Metformin (MET) is used as positive control. Values expressed are means ± S.D of triplicate measurements. For same antioxidant activity with various treatment groups, superscripts in the different bar with different alphabets (a–e) were significantly different ( ). Superscripts with same alphabets were not significantly different between the treated groups ( ). GPx is glutathione peroxidase; CAT is catalase; SOD is superoxide dismutase; LPO is lipid peroxidation.

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.