Evidence-Based Complementary and Alternative Medicine

Research Article

Evaluation on the Pharmacological Effect of Traditional Chinese Medicine SiJunZiTang on Stress-Induced Peptic Ulcers

Table 4

(a) Content changes of monoamine. (b) Content changes of monoamine metabolite.

(a)


Brain	Reagents	N A	D A	5-HT

Cortex	Dist. H₂O 5.0 mL/kg	40.9 ± 2.3	102.4 ± 3.7	50.3 ± 2.2
	SJZT 500 mg/kg	31.3 ± 1.4	86.2 ± 3.3	34.1 ± 4.9
	SJZT1000 mg/kg	17.3 ± 1.1*	62.8 ± 5.6*	25.9 ± 2.8*

Brain stem	Dist. H₂O 5.0 mL/kg	47.9 ± 0.9	131.7 ± 3.4	57.2 ± 3.1
	SJZT 500 mg/kg	41.6 ± 0.3	79.4 ± 1.9*	39.2 ± 0.8*
	SJZT 1000 mg/kg	35.6 ± 0.5	77.8 ± 2.1*	35.1 ± 1.8*

P < 0.05; mean ± S.E.; ; peroral, ng/g (wet weight); control group: Dist. O 5.0 mL/kg (B.W.).

(b)


Brain	Reagents	HVA	5-HIAA	VMA

Cortex	Dist. H₂O 5.0 mL/kg	7.2 ± 0.4	48.2 ± 2.5	10.2 ± 0.9
	SJZT 500 mg/kg	8.1 ± 0.2	48.2 ± 1.7	10.9 ± 1.8
	SJZT1000 mg/kg	6.8 ± 0.3	21.3 ± 0.8*	10.1 ± 1.3

Brain stem	Dist. H₂O 5.0 mL/kg	7.2 ± 0.4	48.2 ± 2.5	10.2 ± 0.9
	SJZT 500 mg/kg	7.8 ± 0.7	80.4 ± 1.6*	8.9 ± 0.2
	SJZT 1000 mg/kg	6.6 ± 0.4	73.8 ± 1.0	7.6 ± 0.3

P < 0.05; mean ± S.E.; N = 6; peroral, ng/g (wet weight).