Research Article
Combining Oxymatrine or Matrine with Lamivudine Increased Its Antireplication Effect against the Hepatitis B Virus In Vitro
Table 3
The inhibition rates of lamivudine combined with matrine or oxymatrine to the intracellular concentrations of HBV-DNA on the 9th experimental day.
| | Drugs (g/mL) | Inhibition (%) | Drugs (g/mL) | Inhibition (%) |
| | 3TC(30) | 79 | | | | 3TC(100) | 97 | | | | Matrine (100) | — | Oxymatrine (100) | — | | Matrine (200) | 39 | Oxymatrine (200) | — | | Matrine (400) | 59 | Oxymatrine (400) | 20 | | Matrine (800) | 94 | Oxymatrine (800) | 71 | | Matrine + 3TC (100 + 30) | 94 | Oxymatrine + 3TC (100 + 30) | 98 | | Matrine + 3TC (200 + 30) | 95 | Oxymatrine + 3TC (200 + 30) | 95 | | Matrine + 3TC (400 + 30) | 95 | Oxymatrine + 3TC (400 + 30) | 98 |
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—: the values are below zero.
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