Bai-Hu-Tang, Ancient Chinese Medicine Formula, May Provide a New Complementary Treatment Option for Sepsis

Table 1

Study groups and their interventions.

Groups	Model	Administration (timing)
Sham-control (𝑛 = 6)	Sham operation	Distilled water 1 mL as vehicle (6 hrs after operation)
Sepsis-control (𝑛 = 6)	CLP	Distilled water 1 mL as vehicle (6 hrs after CLP)
CLP + BHT-L6 (0.45 g/kg) (𝑛 = 6)	CLP	BHT 0.5 mL + distilled 0.5 mL (6 hrs after CLP)
CLP + BHT-H6 (0.9 g/kg) (𝑛 = 6)	CLP	BHT 1 mL (6 hrs after CLP)
CLP + BHT-L12 (0.45 g/kg) (𝑛 = 6)	CLP	BHT 0.5 mL + distilled 0.5 mL (12 hrs after CLP)
CLP + BHT-H12 (0.9 g/kg) (𝑛 = 6)	CLP	BHT 1 mL (12 hrs after CLP)

CLP: rats received cecal ligation and puncture.
BHT-L₆: low dose of BHT was orally administered 6 hrs postoperatively.
BHT-H₆: high dose of BHT was orally administered 6 hrs postoperatively.
BHT-L₁₂: low dose of BHT was orally administered 12 hrs postoperatively.
BHT-H₁₂: high dose of BHT was orally administered 12 hrs postoperatively.