A Drug-Target Network-Based Approach to Evaluate the Efficacy of Medicinal Plants for Type II Diabetes Mellitus

Table 1

List of 33 proteins related with T2DM for molecular docking.

Index	UniProt entry	PDB entry	Protein name
1	O43451	3CTT	Maltase-glucoamylase, intestinal
2	P01308	1TYM	Insulin
3	P01375	2AZ5	Tumor necrosis factor alpha
4	P04150	3H52	Glucocorticoid receptor
5	P04746	1XDO	Pancreatic alpha-amylase
6	P05121	3UT3	Plasminogen activator inhibitor 1
7	P06213	3EKN	Insulin receptor
8	P07339	1LYW	Cathepsin D
9	P08069	3I81	Insulin-like growth factor 1 receptor
10	P11474	3K6P	Steroid hormone receptor ERR1
11	P12821	3L3N	Angiotensin-converting enzyme
12	P13569	3GD7	Cystic fibrosis transmembrane conductance regulator
13	P14410	3LPP	Sucrase-isomaltase, intestinal
14	P14618	3BJF	Pyruvate kinase isozymes M1/M2
15	P14735	3E4A	Insulin-degrading enzyme
16	P19367	1DGK	Hexokinase-1
17	P27361	2ZOQ	Mitogen-activated protein kinase 3
18	P27487	3G0D	Dipeptidyl peptidase 4
19	P27986	4A55	Phosphatidylinositol 3-kinase regulatory subunit alpha
20	P28482	3I5Z	Mitogen-activated protein kinase 1
21	P30613	2VGF	Pyruvate kinase isozymes R/L
22	P35557	3IMX	Glucokinase
23	P35568	2Z8C	Insulin receptor substrate 1
24	P37231	3H0A	Peroxisome proliferator-activated receptor gamma
25	P42336	3HHM	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
26	P42345	1FAP	Serine/threonine-protein kinase mTOR
27	P43220	3C59	Glucagon-like peptide 1 receptor
28	P45983	3PZE	Mitogen-activated protein kinase 8
29	P45984	3NPC	Mitogen-activated protein kinase 9
30	P48736	3SD5	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
31	P53779	3TTI	Mitogen-activated protein kinase 10
32	P62508	2P7A	Estrogen-related receptor gamma
33	Q9BYF1	1R4L	Angiotensin-converting enzyme 2