Antiobesity Effect of Codonopsis lanceolata in High-Calorie/High-Fat-Diet-Induced Obese Rats

Table 3

Effects of water extracts of wild and cultivated Codonopsis lanceolata on body weight, food efficiency ratio, and food intake in SD rats fed with normal or high-fat diets.

Group	Body weight (g)		Food efficiency ratio^1	Food intake (g/day)
	Initial	Final
ND	213.7±10.11	481.60±35.68^##	0.21±0.03^#	57.24±8.17^#
ND + wCL 900 mg/kg	213.6±8.97	473.40±26.38^##	0.17±0.05^*##	55.14±10.06^#
ND + cCL 900 mg/kg	213.6±8.11	484.20±26.15^##	0.22±0.04	57.47±12.33^#
HFD	213.6±7.89	546.80±36.84 **	0.24±0.05 *	71.46±6.80 *
HFD + Sibutramine	213.6±7.87	474.00±30.20^##	0.14±0.03^**##	42.72±6.56^*##
HFD + wCL 100 mg/kg	213.6±7.66	516.22±32.73 *	0.21±0.05^#	52.60±5.42^#
HFD + wCL 300 mg/kg	213.6±7.50	524.22±58.10 *	0.22±0.07	49.92±11.57^##
HFD + wCL 900 mg/kg	213.6±7.70	499.75±30.32^#	0.17±0.08^*##	46.35±10.68^*##
HFD + cCL 100 mg/kg	213.6±7.55	504.20±31.20^#	0.26±0.06 *	48.85±4.38^##
HFD + cCL 300 mg/kg	213.6±7.55	509.33±36.86^#	0.22±0.04	47.37±6.50^##
HFD + cCL 900 mg/kg	213.6±7.05	520.75±22.52 *	0.17±0.08^*##	50.28±9.09^##

¹Food efficiency ratio (FER) = increased body weight (g)/Food intake (g).
Values are the means ± S.D. (𝑛=10), *𝑃<0.05, **𝑃<0.01 versus ND group, ^#𝑃<0.05, ^##𝑃<0.01 versus HFD group.