Antiobesity Effect of Codonopsis lanceolata in High-Calorie/High-Fat-Diet-Induced Obese Rats

Table 4

Effects of water extracts of wild and cultivated Codonopsis lanceolata on retroperitoneal, epididymal, brown fat, and total abdominal fat in SD rats fed with normal or high-fat diets.

Group	Retroperitoneal (g)	Epididymal (g)	Brown fat (g)	Total abdominal (g)
ND	6.21±3.30^##	9.40±4.00^##	0.43±0.08	13.80±4.05^##
ND + wCL 900 mg/kg	5.89±1.69^##	9.76±2.63^##	0.54±0.16	14.50±2.92^##
ND + cCL 900 mg/kg	6.24±1.20^##	9.95±3.36^##	0.52±0.11	14.58±3.09^##
HFD	11.01±1.79 **	15.19±2.57 **	0.44±0.10	25.78±3.67 **
HFD + Sibutramine	6.81±1.54^##	11.16±3.89^#	0.33±0.07	18.60±2.86^*#
HFD + wCL 100 mg/kg	8.88±1.20^*#	15.77±4.34 **	0.40±0.07	23.26±3.12 **
HFD + wCL 300 mg/kg	8.69±0.83^*#	13.42±1.36 *	0.53±0.12	21.94±4.84 **
HFD + wCL 900 mg/kg	8.25±1.69^*#	12.67±3.79^*#	0.64±0.10^**##	19.91±4.46^*#
HFD + cCL 100 mg/kg	9.61±2.28 *	13.12±2.01 *	0.54±0.07	20.73±5.21^*#
HFD + cCL 300 mg/kg	10.60±2.23 *	14.58±3.10 **	0.67±0.11^**##	24.23±5.71 **
HFD + cCL 900 mg/kg	9.99±3.10 *	14.10±3.81 **	0.56±0.20 **	22.82±3.23 **

Values are means ± S.D. (𝑛=10), *𝑃<0.05, **𝑃<0.01 versus ND group, ^#𝑃<0.05, ^##𝑃<0.01 versus HFD group.