Review Article
ZHENG-Omics Application in ZHENG Classification and Treatment: Chinese Personalized Medicine
Table 1
Clinical researches of TCM ZHENGs with systems biology.
| Syndromes | Disease | Researchers | Omics |
| Liver-gallbladder dampness-heat | Hypertension | Chu et al. [22] | Proteomics | Chronic hepatitis B | Guo et al. [23] | |
| Liver Yang transforming into wind | Cerebral infarction | Zeng et al. [24] | Proteomics |
| Liver stagnation | Depression, premenstrual syndrome, menopausal syndrome | Tan et al. [25] | Proteomics |
| | Rheumatoid arthritis | Lu et al. [26] | Genomics | Cold and heat pattern | Cold-syndrome genealogy | Wang et al. [27] | Genomics | | Rheumatoid arthritis | Gu et al. [28] | Metabolomics |
| | Colorectal cancer | Yang et al. [29] | Genomics | Spleen deficiency | Chronic superficial gastritis | Yang et al. [30] | Genomics | | Gastritis | Liu et al. [31] | Proteomics |
| | Diabetes | Weng et al. [32] | Genomics | | | Wu et al. [11] | Genomics | Kidney deficiency | Normal | Ni et al. [12] | Genomics | | Normal | Liu et al. [14] | Proteomics | | Chronic heart failure | Zheng et al. [33] | Metabolomics |
| Dampness syndrome | Chronic hepatitis B | Guan et al. [34] | Genomics | Chronic gastritis | Wang et al. [35] | Proteomics |
| Dampness-phlegm | Obesity | Wang et al. [36] | Genomics |
| | Coronary heart disease | Ma et al. [37] | Genomics | | Coronary heart disease | Yuan et al. [38] | Genomics | Blood stasis | Coronary heart disease | Yuan et al. [39] | Genomics | | Coronary heart disease | Wu et al. [40] | Proteomics | | Unstable angina | Wang et al. [41] | Metabolomics |
| | Hepatitis B cirrhosis | Li et al. [42] | Genomics | | Chronic hepatitis B | Song et al. [43] | Proteomics | Deficiency syndrome | Primary liver cancer | Chen et al. [44] | Metabolomics | | Diabetes mellitus | Wu et al. [45] | Metabolomics | | Hypertension | Yang et al. [46] | Metabolomics |
| Liver-kidney Yin deficiency syndrome | Hepatocellular carcinoma | Weng et al. [47] | Genomics |
| Ascendant hyperactivity of Ganyang syndrome | Hypertension | Jiang et al. [48] | Metabolomics |
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