A Promise in the Treatment of Endometriosis: An Observational Cohort Study on Ovarian Endometrioma Reduction by N-Acetylcysteine

Table 2

Endometriomas size at enrollment and at the end of observation.

	Controls; (𝑛=72)	Treated; (𝑛=73)	𝑃
Average diameter (mm)
Initial	31.6 ± 18.4	26.9 ± 14.9	ns
Final	38.3 ± 23.2	25.4 ± 17.8	<0.001
Difference	6.62 ± 16.14	−1.53 ± 11.43	0.001
Average volume (mL)
Initial	35.1 ± 62.6	20.4 ± 31.3	ns
Final	67.3 ± 123.2	23.6 ± 48.6	0.006
Difference	32.1 ± 89.9	3.20 ± 32.7	0.012
Number of cysts
Increased	42 (58%); (7 newly formed)	20 (27%); (4 newly formed)	<0.001*
Decreased	20 (28%); (4 disappeared)	45 (62%); (8 disappeared)
Unchanged	10 (14%)	8 (11%)

∗At the Pearson’s chi-square test.