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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 241629, 6 pages
http://dx.doi.org/10.1155/2013/241629
Research Article

Therapeutic Effects of Saireito (Chai-Ling-Tang), a Traditional Japanese Herbal Medicine, on Lymphedema Caused by Radiotherapy: A Case Series Study

1Department of Therapeutic Radiology, Ishikawa Prefectural Central Hospital, Kanazawa, Ishikawa 920-8530, Japan
2Department of Radiology, Nagoya City University, Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi 467-8601, Japan
3Clinic of Japanese-Oriental (Kampo) Medicine, Department of Otorhinolaryngology-Head and Neck Surgery, Kanazawa University Hospital, Kanazawa, Ishikawa 920-8641, Japan

Received 25 March 2013; Accepted 21 May 2013

Academic Editor: Yoshiharu Motoo

Copyright © 2013 Aiko Nagai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. R. Casley-Smith, C. T. Wang, J. R. Casley-Smith, and C. Zi-Hai, “Treatment of filarial lymphoedema and elephantiasis with 5,6-benzo-α-pyrone (coumarin),” British Medical Journal, vol. 307, no. 6911, pp. 1037–1041, 1993. View at Google Scholar · View at Scopus
  2. C. Badger, K. Seers, N. Preston, and P. Mortimer, “Antibiotics/anti-inflammatories for reducing acute inflammatory episodes in lymphoedema of the limbs,” Cochrane Database of Systematic Reviews, no. 2, Article ID CD003143, 2004. View at Google Scholar · View at Scopus
  3. C. L. Loprinzi, J. Sloan, and J. Kugler, “Coumarin-induced hepatotoxicity,” Journal of Clinical Oncology, vol. 15, no. 9, pp. 3167–3168, 1997. View at Google Scholar · View at Scopus
  4. C. M. Badger, J. L. Peacock, and P. S. Mortimer, “A randomized, controlled, parallel-group clinical trial comparing multilayer bandaging followed by hosiery versus hosiery alone in the treatment of patients with lymphedema of the limb,” Cancer, vol. 88, no. 12, pp. 2832–2837, 2000. View at Google Scholar
  5. R. Hornsby, “The use of compression to treat lymphoedema,” Professional Nurse, vol. 11, no. 2, pp. 127–128, 1995. View at Google Scholar · View at Scopus
  6. G. Bertelli, M. Venturini, G. Forno, F. Macchiavello, and D. Dini, “Conservative treatment of postmastectomy lymphedema: a controlled, randomized trial,” Annals of Oncology, vol. 2, no. 8, pp. 575–578, 1991. View at Google Scholar · View at Scopus
  7. A. F. Williams, A. Vadgama, P. J. Franks, and P. S. Mortimer, “A randomized controlled crossover study of manual lymphatic drainage therapy in women with breast cancer-related lymphoedema,” European Journal of Cancer Care, vol. 11, no. 4, pp. 254–261, 2002. View at Publisher · View at Google Scholar · View at Scopus
  8. L. Andersen, I. Hojris, M. Erlandsen, and J. Andersen, “Treatment of breast-cancer-related lymphedema with or without manual lymphatic drainage: a randomized study,” Acta Oncologica, vol. 39, no. 3, pp. 399–405, 2000. View at Google Scholar · View at Scopus
  9. K. Ogawa-Ochiai, M. Ogawa, and Y. Motoo, Traditional Medicine: New Research, Chapter 1, Nova Science, New York, NY, USA, 2012.
  10. H. Yasunaga, H. Miyata, H. Horiguchi, K. Kuwabara, H. Hashimoto, and S. Matsuda, “Effect of the Japanese herbal kampo medicine Dai-kenchu-to on postoperative adhesive small bowel obstruction requiring long-tube decompression: a propensity score analysis,” Evidence-Based Complementary and Alternative Medicine, vol. 2011, Article ID 264289, 7 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. T. Kono, N. Mamiya, N. Chisato et al., “Efficacy of goshajinkigan for peripheral neurotoxicity of oxaliplatin in patients with advanced or recurrent colorectal cancer,” Evidence-Based Complementary and Alternative Medicine, vol. 2011, Article ID 418481, 8 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  12. N. Fujitsuka, K. Goto, S. Takeda, and M. Aburada, “The diuretic effect of sairei-to is mediated by nitric oxide production in pentobarbital-anesthetized rats,” Journal of Pharmacological Sciences, vol. 94, no. 2, pp. 185–191, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. T. Hattori, H. Maruyama, H. Nishimura et al., “Effects of Saireito, a Japanese herbal medicine, on edema via antagonistic actions against aldosterone in anti-GBM nephritic rats,” Clinical and Experimental Nephrology, vol. 10, no. 1, pp. 13–18, 2006. View at Publisher · View at Google Scholar · View at Scopus
  14. C. Y. Leung, L. Liu, R. N. S. Wong, Y. Y. Zeng, M. Li, and H. Zhou, “Saikosaponin-d inhibits T cell activation through the modulation of PKCθ, JNK, and NF-κB transcription factor,” Biochemical and Biophysical Research Communications, vol. 338, no. 4, pp. 1920–1927, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. S. Webb, “Optimizing the planning of intensity-modulated radiotherapy,” Physics in Medicine and Biology, vol. 39, no. 12, pp. 2229–2246, 1994. View at Publisher · View at Google Scholar · View at Scopus
  16. Y. Kishida, H. Miki, T. Nishii et al., “Therapeutic effects of Saireito (TJ-114), a traditional Japanese herbal medicine, on postoperative edema and inflammation after total hip arthroplasty,” Phytomedicine, vol. 14, no. 9, pp. 581–586, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. P. Rubin and G. W. Casarett, “Clinical radiation pathology as applied to curative radiotherapy,” Cancer, vol. 22, no. 4, pp. 767–778, 1968. View at Google Scholar · View at Scopus
  18. A. Fiebeler and F. C. Luft, “The mineralocorticoid receptor and oxidative stress,” Heart Failure Reviews, vol. 10, no. 1, pp. 47–52, 2005. View at Publisher · View at Google Scholar · View at Scopus
  19. Y. Sun, J. Zhang, L. Lu, S. S. Chen, M. T. Quinn, and K. T. Weber, “Aldosterone-induced inflammation in the rat heart: role of oxidative stress,” American Journal of Pathology, vol. 161, no. 5, pp. 1773–1781, 2002. View at Google Scholar · View at Scopus
  20. M. Bond, R. P. Fabunmi, A. H. Baker, and A. C. Newby, “Synergistic upregulation of metalloproteinase-9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF-κB,” FEBS Letters, vol. 435, no. 1, pp. 29–34, 1998. View at Publisher · View at Google Scholar · View at Scopus
  21. S. K. Hansen, C. Nerlov, U. Zabel et al., “A novel complex between the p65 subunit of NF-κB and c-Rel binds to a DNA element involved in the phorbol ester induction of the human urokinase gene,” EMBO Journal, vol. 11, no. 1, pp. 205–213, 1992. View at Google Scholar · View at Scopus
  22. C. Kunsch and C. A. Rosen, “NF-κB subunit-specific regulation of the interleukin-8 promoter,” Molecular and Cellular Biology, vol. 13, no. 10, pp. 6137–6146, 1993. View at Google Scholar · View at Scopus
  23. T. Yokoo and M. Kitamura, “Dual regulation of IL-1β-mediated matrix metalloproteinase-9 expression in mesangial cells by NF-KB and AP-1,” American Journal of Physiology, vol. 270, no. 1, pp. F123–F130, 1996. View at Google Scholar · View at Scopus
  24. S. Yoshida, M. Ono, T. Shono et al., “Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis,” Molecular and Cellular Biology, vol. 17, no. 7, pp. 4015–4023, 1997. View at Google Scholar · View at Scopus
  25. I. Iwai, T. Suda, F. Tozawa et al., “Stimulatory effect of Saireito on proopiomelanocortin gene expression in the rat anterior pituitary gland,” Neuroscience Letters, vol. 157, no. 1, pp. 37–40, 1993. View at Publisher · View at Google Scholar · View at Scopus
  26. Y. Nakano, T. Suda, F. Tozawa et al., “Saireito (a Chinese herbal drug)-stimulated secretion and synthesis of pituitary ACTH are mediated by hypothalamic corticotropin-releasing factor,” Neuroscience Letters, vol. 160, no. 1, pp. 93–95, 1993. View at Publisher · View at Google Scholar · View at Scopus
  27. “Package insert of TSUMURA Saireito Extract Granules for Ethical Use, Tsumura & co,” 2012, http://plaza.umin.ac.jp/~kconsort/framepage.html.
  28. E. C. Rosenow III, “The spectrum of drug-induced pulmonary disease,” Annals of Internal Medicine, vol. 77, no. 6, pp. 977–991, 1972. View at Google Scholar · View at Scopus
  29. A. Kondo, “Drug-induced pneumonitis,” Kekkaku, vol. 74, no. 1, pp. 33–41, 1999 (Japanese). View at Google Scholar · View at Scopus
  30. O. Sakamoto, K. Ichikado, H. Kohrogi, and M. Suga, “Clinical and CT characteristics of Chinese medicine-induced acute respiratory distress syndrome,” Respirology, vol. 8, no. 3, pp. 344–350, 2003. View at Publisher · View at Google Scholar · View at Scopus
  31. A. Daibo, Y. Yoshida, S. Kitazawa, Y. Kosaka, T. Bando, and M. Sudo, “A case of pneumonitis and hepatic injury caused by a herbal drug (Sho-saiko-to),” Japanese Journal of Thoracic Diseases, vol. 30, no. 8, pp. 1583–1588, 1992 (Japanese). View at Google Scholar · View at Scopus
  32. K. Nakagawa, M. Miyajima, and M. Ando, “Drug-induced pneumonitis,” Rinsho-I, vol. 24, pp. 2425–2429, 1998 (Japanese). View at Google Scholar
  33. R. Temaru, N. Yamashita, S. Matsui, T. Ohta, A. Kawasaki, and M. Kobayashi, “A case of drug induced pneumonitis caused by Saiboku-to,” Japanese Journal of Thoracic Diseases, vol. 32, no. 5, pp. 485–490, 1994. View at Google Scholar · View at Scopus
  34. “Package insert of TSUMURA shosaikoto extract granules for ethical use, Tsumura & co,” 2007, http://plaza.umin.ac.jp/~kconsort/framepage.html.