Catechins and Sialic Acid Attenuate Helicobacter pylori-Triggered Epithelial Caspase-1 Activity and Eradicate Helicobacter pylori Infection

Figure 4

Effects of catechins (CAs) and/or sialic acid (SA) on gastritis scores and bacterial counts in the H. pylori-infected mouse model. Each group of mice was treated with different dosage of CA and/or SA (UC, uninfected control, 𝑛=10; IC, infected control, 𝑛=20; TT, triple therapy, 𝑛=20; CA7, CA solution for 7 days, 𝑛=20; SA7, SA solution for 7 days, 𝑛=20; and CASA7, 10, and 14, CASA solution for 7, 10, and 14 days, resp., 𝑛=40). Each column with a vertical line represents mean ± SD. ^∗𝑃<0.05, compared to UC; ^#𝑃≤0.01, compared to IC; ^§𝑃<0.05, compared to TT.

(a)

(b)