Catechins and Sialic Acid Attenuate Helicobacter pylori-Triggered Epithelial Caspase-1 Activity and Eradicate Helicobacter pylori Infection
Table 1
Treatment regimens and eradication rates among various groups of mice infected by H. pylori.
Group
Name
Treatment regimen1
H. pylori (+)/(−)
Eradication2
Exp1
Exp2
rate (%)
A
UC (uninfected control)
10
—
0/5
0/5
NA
B
IC (infected control)
20
—
10/0
10/0
0
C
TT (treatment control 1)
20
Triple therapy for 7 days
1/9
1/9
90*
D
CA7 (treatment control 2)
20
CA solution for 7 days
10/0
9/1
5
E
SA7 (treatment control 3)
20
SA solution for 7 days
9/1
10/0
5
F
CASA7
40
CASA solution for 7 days
6/14
4/16
75*
G
CASA10
40
CASA solution for 10 days
1/19
1/19
95*#
H
CASA14
40
CASA solution for 14 days
1/19
1/19
95*#
CA solution, 1% glucose and 640 mg/L CA; SA solution, 1% glucose and 160 mg/L SA; CASA solution, 1% glucose and a mixture of 640 mg/L CA and 160 mg/L SA. NA: not available. *P < 0.001, compared to the CA7 or SA7 group; #P = 0.01, compared to the CASA7 group.
