Topical Treatment of Nonhealing Venous Leg Ulcer with Propolis Ointment

Table 4

Mean ulceration area (cm²) according to the duration of treatment.

Duration of treatment	Group 1		Group 2		Statistical; significance; between groups
	Ulceration area	𝑁	Ulceration area	𝑁
Before	8.35 ± 0.72^a	28	8.29 ± 0.80^a	28	NS
1 week	6.42 ± 0.82^a	24	6.87 ± 0.69^a	28	NS
2 weeks	5.00 ± 0.89^a	20	5.94 ± 0.73^a	28	𝑃<0.001
3 weeks	3.44 ± 0.72^a	12	5.36 ± 0.73^a	28	𝑃<0.001
4 weeks	1.98 ± 0.88^a	8	5.10 ± 0.76	22	𝑃<0.001
5 weeks	0.72 ± 0.22^a	3	5.19 ± 0.81	22	𝑃<0.001
6 weeks	0.00	0	5.24 ± 0.88	22
7 weeks			5.21 ± 1.06^a	22
8 weeks			4.61 ± 1.2^a	17
9 weeks			4.02 ± 1.22^a	17
10 weeks			3.11 ± 1.12^a	17
11 weeks			2.24 ± 1.09^a	17
12 weeks			1.54 ± 0.89^a	12
13 weeks			0.98 ± 0.49	12
14 weeks			0.74 ± 0.30^a	7
15 weeks			0.38 ± 0.06^a	3
16 weeks			0.00	0

Statistical significance ^aP < 0.005 compared with the next week following day of measurement.