In Vitro Morphological Assessment of Apoptosis Induced by Antiproliferative Constituents from the Rhizomes of Curcuma zedoaria
Table 4
Percentage of necrotic cells (%).
Cell lines
Compounds
12.5 μg/mL
25 μg/mL
40 μg/mL
50 μg/mL
MCF-7
Curzerenone
2.00 ± 1.30a
3.83 ± 0.60b
5.50 ± 1.30c
17.83 ± 2.60d
Alismol
3.83 ± 0.30a
5.17 ± 1.50b
38.33 ± 1.30c
58.97 ± 1.10d
Ca Ski
Curzerenone
3.50 ± 1.30a
5.57 ± 1.10b
11.83 ± 2.10c
16.33 ± 1.0d
Alismol
5.83 ± 1.50a
14.00 ± 3.50b
45.33 ± 0.60c
60.33 ± 1.00d
HCT-116
Curzerenone
9.00 ± 1.50a
15.33 ± 0.80b
25.00 ± 0.50c
28.00 ± 0.50d
Alismol
19.50 ± 1.00a
26.00 ± 1.30b
67.67 ± 2.60c
76.67 ± 0.80d
Values expressed are mean ± standard deviation (SD) of triplicate measurements. For the compounds with the different concentration, means in the same rows with different letters (a–d) were significantly different ().