BlueBerry Isolate, Pterostilbene, Functions as a Potential Anticancer Stem Cell Agent in Suppressing Irradiation-Mediated Enrichment of Hepatoma Stem Cells

Figure 2

CD133⁺ Mahlavu cells exhibited cancer-stem like cell properties. (a) CD133⁺ Mahlavu cells exhibited a higher ability to form cell aggregates and/or tumor spheroids. (b) CD133⁺ and parental Mahlavu cells were irradiated with 2 different doses (1 and 5 Gy). CD133⁺ Mahlavu cells demonstrated increased resistance against irradiation as compared to CD133-counterparts. (c) CD133⁺ Mahlavu cells were also significantly more invasive than their CD133-counterparts. Bars: 50 μm.

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(b)

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