Research Article

Caffeic Acid Phenethyl Ester Inhibits Epithelial-Mesenchymal Transition of Human Pancreatic Cancer Cells

Figure 5

Expression of signaling molecules related to EMT. By real-time PCR expression, Snail 1 was upregulated by TGF-β, but it was not affected by CAPE treatment. By immunocytochemistry stain, the nuclear expression of Twist 2 was enhanced by TGF-β (44%), and this effect could be reversed by CAPE (12%).
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(a) Expression of Snail 1
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(b) Expression of Twist 2