Evidence-Based Complementary and Alternative Medicine

Research Article

Hepatoprotective Effect of Fermented Soybean (Nutrient Enriched Soybean Tempeh) against Alcohol-Induced Liver Damage in Mice

Table 1

Serum biochemical parameter of liver protective effect of different experimental group.


Treatment	ALT (U/L)¹	AST (U/L)¹	Cholesterol (mmol/L)¹	TG (mmol/L)¹

Normal control (PBS)	14.09 ± 1.53^a	98.16 ± 1.99^a	3.14 ± 0.39^a	1.48 ± 0.23^a
Ethanol control (50% ETOH + PBS)	48.11 ± 1.78	367.30 ± 1.10	4.83 ± 0.3	3.87 ± 0.3
Positive control (50% ETOH + silybin (50 mg/kg))	26.72 ± 1.20^a	171.70 ± 3.79^a	4.11 ± 0.8^a	2.53 ± 0.4^a
50% ETOH + SBE (200 mg/kg)	35.14 ± 4.50^a	183.28 ± 7.28^a	3.26 ± 0.11^a	2.16 ± 0.16^a
50% ETOH + SBE (1000 mg/kg)	25.85 ± 6.49	174.49 ± 1.15	2.99 ± 0.29^a	2.03 ± 0.01^a
50% ETOH + NESTE (200 mg/kg)	23.28 ± 4.50^a	168.39 ± 3.42^a	3.22 ± 0.26^a	2.88 ± 0.26^a
50% ETOH + NESTE (1000 mg/kg)	18.50 ± 3.00^a	157.62 ± 3.53^a	3.08 ± 0.44^a	1.94 ± 1.85^a

Values are expressed as mean ± S.E.M (), ^avalues are significantly different from ethanol control (), ALT: alanine transaminase, AST: aspartate transaminase, TG: triglyceride.