Hepatoprotective Effect of Fermented Soybean (Nutrient Enriched Soybean Tempeh) against Alcohol-Induced Liver Damage in Mice

Table 2

Liver protective effect on liver homogenate parameters of different experimental groups.

Treatment	MDA; (nmol/g protein)^1	NO; (µM/mg protein)^1	SOD; (U/mg protein)^1	FRAP; (mM FeII/mg protein)^1
Normal control (PBS)	3.20 ± 0.22^a	10.13 ± 0.18^a	17.17 ± 0.74^a	9.42 ± 1.0^a
Ethanol control (50% ETOH + PBS)	7.25 ± 0.08	15.09 ± 0.86	12.46 ± 2.51	5.28 ± 0.01
Positive control (50% ETOH + silybin (50 mg/kg))	4.95 ± 0.08^a	10.20 ± 3.08^a	18.54 ± 0.37^a	15.02 ± 0.07^a
50% ETOH + SBE (200 mg/kg)	3.02 ± 0.25^a	9.55 ± 0.35^a	19.38 ± 0.10^a	6.59 ± 0.03
50% ETOH + SBE (1000 mg/kg)	2.93 ± 0.34^a	9.54 ± 0.04^a	20.08 ± 1.58^a	6.24 ± 0.04
50% ETOH + NESTE (200 mg/kg)	2.22 ± 0.17^a	9.55 ± 0.58^a	19.44 ± 0.67^a	9.42 ± 0.02^a
50% ETOH + NESTE (1000 mg/kg)	1.34 ± 0.23^a	8.45 ± 0.27^a	20.53 ± 0.24^a	12.78 ± 0.10^a

1Values are expressed as mean ± S.E.M (𝑛=8), ^avalues are significantly different from ethanol control (𝑃<0.05), MDA: malondialdehyde, NO: nitric oxide, SOD: superoxide dismutase, FRAP: ferric reducing antioxidant power.