Vitexicarpin Acts as a Novel Angiogenesis Inhibitor and Its Target Network

<table>Vitexicarpin inhibits VEGF-induced proliferation of endothelial cells. (a) Vitexicarpin inhibits VEGF-induced endothelial cells viability in a dose-dependent manner. Cell viability was quantified by CCK-8 assay. (b) Effects of vitexicarpin at indicated concentrations on endothelial cells viability under normal culture conditions. (c) Cell cycle analysis showing G2/M arrest in cells treated with vitexicarpin at indicated concentrations. <svg height="13.95" id="M12" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 73.300003 13.95" width="73.300003" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared with VEGF control.</table>

Evidence-Based Complementary and Alternative Medicine

fig3

Figure 3

Figure 3: Vitexicarpin Acts as a Novel Angiogenesis Inhibitor and Its Target Network 