Figure 3: Vitexicarpin inhibits VEGF-induced proliferation of endothelial cells. (a) Vitexicarpin inhibits VEGF-induced endothelial cells viability in a dose-dependent manner. Cell viability was quantified by CCK-8 assay. (b) Effects of vitexicarpin at indicated concentrations on endothelial cells viability under normal culture conditions. (c) Cell cycle analysis showing G2/M arrest in cells treated with vitexicarpin at indicated concentrations. ; compared with VEGF control.