A Small Molecule Swertisin from Enicostemma littorale Differentiates NIH3T3 Cells into Islet-Like Clusters and Restores Normoglycemia upon Transplantation in Diabetic Balb/c Mice
Figure 10
RT-PCR and Q-PCR expression data of various stem/progenitor and islet differentiation pathway genes. (a) shows mRNA expression of various stem/progenitor genes and key islet differentiation pathway transcription factor genes harvested at 10 days of differentiation protocol in SFM alone, activin A, and swertisin-mediated ILCC. (b) shows comparative PDX-1 transcript expression in differentiated clusters harvested at different timepoints. (c) represents insulin mRNA transcript levels in , activin A, and swertisin-induced clusters at the 8th day.
