A Small Molecule Swertisin from <i>Enicostemma littorale</i> Differentiates NIH3T3 Cells into Islet-Like Clusters and Restores Normoglycemia upon Transplantation in Diabetic Balb/c Mice

<table>Comparative montage of morphological events occurring in 3–8 day time duration. The figure represents day-wise representation of morphological changes and differentiation event occurring with SFM, activin A and swertisin-mediated ILCC. The figure also shows DTZ staining in differentiated ILCC for primary confirmation of beta cell differentiation and C-peptide staining representing presence of insulin biogenesis and insulin granules.</table>

Evidence-Based Complementary and Alternative Medicine

fig8

Figure 8

Figure 8: A Small Molecule Swertisin from <i>Enicostemma littorale</i> Differentiates NIH3T3 Cells into Islet-Like Clusters and Restores Normoglycemia upon Transplantation in Diabetic Balb/c Mice 

Figure 8 | A Small Molecule Swertisin from Enicostemma littorale Differentiates NIH3T3 Cells into Islet-Like Clusters and Restores Normoglycemia upon Transplantation in Diabetic Balb/c Mice 