Research Article

Cytotoxicity and Modes of Action of the Methanol Extracts of Six Cameroonian Medicinal Plants against Multidrug-Resistant Tumor Cells

Figure 3

Effect of plant extracts and vinblastine (VIN) on the MMP of CCRF-CEM cells after 24 h of treatment. Data of control and vinblastine under similar experimental conditions were previously reported [33]. Samples were tested at their 1/4 IC50 (1), 1/2 IC50 (2), IC50 (3), and 2 IC50 (4) values. The IC50 values are 0.20 μM for VIN, 10.57 μg/mL (Gladiolus quartinianus whole plant, GQW), 9.28 μg/mL (Vepris soyauxii leaves, VSL), and 17.32 μg/mL (Anonidium mannii leaves, AML).
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