Carvacrol Protects against Hepatic Steatosis in Mice Fed a High-Fat Diet by Enhancing SIRT1-AMPK Signaling
Figure 3
Enhanced hepatic SIRT1-AMPK signaling in CSD-fed mice. (a) Hepatic mRNA expression levels of SIRT1, LXRα, SREBP1c, FAS, leptin, CD36, and CPT1 normalized to GAPDH relative to ND-fed mice. (b) Upper, representative western blot of phospho- and total AMPK in livers of ND, HFD, and CSD-fed mice. Lower, densitometric analysis of AMPK phosphorylation expressed as change relative to each control band. Data are shown as the mean ± SEM, . *.
