Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Tab 5

Research Article

Efficacy of Plectranthus amboinicus (Lour.) Spreng in a Murine Model of Methicillin-Resistant Staphylococcus aureus Skin Abscesses

Table 5

FIC values (FIC) and FIC index (IFIC) of hydroalcoholic extract (a) and the fraction F4 (b) in combination with vancomycin (Van) or ciprofloxacin (Cip) against a standard strain of S. aureus (ATCC 65398) and three randomly chosen MRSA strains. The interaction between the drugs and the plant was additive (A), synergic, (S) or indifferent (I).
(a) Hydroalcoholic extract (EH)

CIFICIFInteractionCIFIFICInteraction
EhVanEhCip

ATCC (65398)112I0.522.5I
MRSA 05123I0.522.5I
MRSA 08112I0.522.5I
MRSA 12112I0.522.5I

(b) Ethyl acetate fraction (F4)

CIFICIFInteractionCIFIFICInteraction
F4VanF4Cip

ATCC (65398)0.50.250.75S0.50.51A
MRSA 050.50.250.75S0.50.51A
MRSA 080.50.250.75S0.50.51A
MRSA 120.50.250.75S0.50.51A

CIF: fractional inhibitory concentration; ICIF: fractional inhibitory concentration index.