Table 5
FIC values (FIC) and FIC index (IFIC) of hydroalcoholic extract (a) and the fraction F4 (b) in combination with vancomycin (Van) or ciprofloxacin (Cip) against a standard strain of S. aureus (ATCC 65398) and three randomly chosen MRSA strains. The interaction between the drugs and the plant was additive (A), synergic, (S) or indifferent (I).
| (a) Hydroalcoholic extract (EH) |
| | CIF | ICIF | Interaction | CIF | IFIC | Interaction | | Eh | Van | Eh | Cip |
| | ATCC (65398) | 1 | 1 | 2 | I | 0.5 | 2 | 2.5 | I | | MRSA 05 | 1 | 2 | 3 | I | 0.5 | 2 | 2.5 | I | | MRSA 08 | 1 | 1 | 2 | I | 0.5 | 2 | 2.5 | I | | MRSA 12 | 1 | 1 | 2 | I | 0.5 | 2 | 2.5 | I |
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| (b) Ethyl acetate fraction (F4) |
| | CIF | ICIF | Interaction | CIF | IFIC | Interaction | | F4 | Van | F4 | Cip |
| | ATCC (65398) | 0.5 | 0.25 | 0.75 | S | 0.5 | 0.5 | 1 | A | | MRSA 05 | 0.5 | 0.25 | 0.75 | S | 0.5 | 0.5 | 1 | A | | MRSA 08 | 0.5 | 0.25 | 0.75 | S | 0.5 | 0.5 | 1 | A | | MRSA 12 | 0.5 | 0.25 | 0.75 | S | 0.5 | 0.5 | 1 | A |
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CIF: fractional inhibitory concentration; ICIF: fractional inhibitory concentration index.
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