Effect of Xiaoyaosan Decoction on Learning and Memory Deficit in Rats Induced by Chronic Immobilization Stress
Figure 4
Effects of XYS on Morris water maze. (a) During the 3-day acquisition training, all the rats displayed progressive decreases in the escape latency to reach the hidden platform. Overall statistic compared by two-way ANOVA did not reveal significant changes, except in the 3rd and 4th acquisition trials (). (b) In the probe trial test performed 24 h after the last acquisition trial, CIS + saline group displayed significant decrease compared with the control group () in duration in target quadrant. CIS + rolipram group and CIS + XYS group displayed significant increase compared with CIS + saline group () in duration in target quadrant. (c) As entries in target quadrant, there are no significant changes in groups. Values shown are means ± SD of ten rats per group. * versus the control group. # versus the CIS + saline group.
