Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Tab 5

Research Article

Curative Effects of ZHENG-Based Fuzheng-Huayu Tablet on Hepatitis B Caused Cirrhosis Related to CYP1A2 Genetic Polymorphism

Table 5

Correlation between CYP1A2 genotypes and FZHY efficacy on Child-Pugh scores in HBC.

GenotypesEffective (%) Invalid (%) OR95% CI

CYP1A2-5347
 CC17 (70.80)63 (75.00)
 CT6 (25.00)20 (23.80)0.8440.8990.312, 2.591
 TT1 (4.20)1 (1.20)0.3930.2700.016, 4.541
 CT + TT7 (29.20)21 (25.00)0.6810.8100.295, 2.221
CYP1A2-2964
 GG10 (41.70)46 (53.50)
 GA11 (45.80)30 (34.90)0.2890.5930.224, 1.567
 AA3 (12.50)10 (11.60)0.7000.7250.168, 3.121
 GA + AA14 (58.30)40 (46.50)0.3060.6210.249, 1.552
CYP1A2-733
 CC3 (12.50)9 (10.50)
 CA9 (37.50)38 (44.20)0.6531.4070.316, 6.277
 AA12 (50.00)39 (45.30)0.9141.0830.252, 4.656
 CA + AA21 (87.50)77 (89.50)0.7771.2220.304, 4.921

The bold font emphasizes the result was statistically significant ( )

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