Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Tab 6

Research Article

Curative Effects of ZHENG-Based Fuzheng-Huayu Tablet on Hepatitis B Caused Cirrhosis Related to CYP1A2 Genetic Polymorphism

Table 6

Correlation between CYP1A2 Genotypes and FZHY efficacy on ZHENG score in HBC.

GenotypesEffective (%) Invalid (%) OR95% CI

CYP1A2-5347
 CC48 (71.60)32 (72.70)
 CT17 (25.40)9 (20.50)0.6240.7940.315, 2.000
 TT0 (0)2 (4.50)
 CT + TT17 (25.40)11 (25.00)0.9470.9710.402, 2.341
CYP1A2-2964
 GG33 (49.30)23 (52.30)
 GA30 (44.80)11 (25.00)0.1460.5260.220, 1.258
 AA3 (4.50)10 (22.70)0.0304.7831.184, 19.321
 GA + AA33 (49.30)21 (47.70)0.8150.9130.426, 1.959
CYP1A2-7330.527
 CC9 (13.40)3 (6.80)
 CA27 (40.30)20 (45.50)0.2662.2220.532, 9.275
 AA30 (44.80)21 (47.70)0.2992.1000.507, 8.694
 CA + AA57 (85.10)41 (93.20)0.2612.1580.550, 8.466

The bold font emphasizes the result was statistically significant ( )

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