Protective Effect of Brazilian Propolis against Liver Damage with Cholestasis in Rats Treated with -Naphthylisothiocyanate
Figure 1
Effects of administered BPEE and VE on serum ALT (a) and AST (b) activities in ANIT-treated rats. Fasted rats in ANIT, ANIT + BPEE(25), ANIT + BPEE(50), ANIT + BPEE(100), and ANIT + VE groups were orally administered with vehicle (Tween 80-EtOH), 25 mg/kg of BPEE, 50 mg/kg of BPEE, 100 mg/kg of BPEE, and 250 mg/kg of VE, respectively, at 12 h after treatment with ANIT dissolved in olive oil (75 mg/kg, i.p.). Fasted rats in Control group were given olive oil and Tween 80-EtOH used as vehicle just before and at 12 h after ANIT treatment, respectively. ALT and AST in serum were assayed at 24 h after ANIT treatment as described in Section 2. Each value is a mean ± S.D. ( for Control group; per each group for all groups with ANIT treatment). * (versus Control group); # (versus ANIT group).
