Figure 6: Effects of quercetin on the reduced phosphorylation of Jak2-Stat3 pathway (a) and the increased expression of Socs3 (b) in fructose-treated INS-1 β-cells. INS-1 β-cells were treated with 1 mM fructose in the absence or presence of 5, 10, and 20 μM quercetin for 24 h. Data were presented as the mean ± SEM of three to six independent experiments. # and ## relative to untreated control cells; * and ** relative to fructose-treated vehicle cells.