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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 309262, 6 pages
http://dx.doi.org/10.1155/2013/309262
Research Article

Xiangshao Granule Exerts Antidepressive Effects in a Depression Mouse Model by Ameliorating Deficits in Hippocampal BDNF and TrkB

1Department of Gastrointestinal Surgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China
2Monash University, Department of Biochemistry and Molecular Biology, Clayton, Victoria 3800, Australia
3Visiting Professor, West China Hospital, Sichuan University, Chengdu 610041, China

Received 9 September 2013; Accepted 13 November 2013

Academic Editor: David Mischoulon

Copyright © 2013 Yi Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. M. Propst, B. J. Quade, R. A. Nowak, and E. A. Stewart, “Granulocyte macrophage colony-stimulating factor in adenomyosis and autologous endometrium,” Journal of the Society for Gynecologic Investigation, vol. 9, no. 2, pp. 93–97, 2002. View at Publisher · View at Google Scholar · View at Scopus
  2. D. J. Kupfer, E. Frank, and M. L. Phillips, “Major depressive disorder: new clinical, neurobiological, and treatment perspectives,” The Lancet, vol. 379, no. 9820, pp. 1045–1055, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. Q. Ge and H. Zhang, “Effects of Chinese herbal medicines for regulating liver qi on expression of 5-hydroxytryptamine 3B receptor in hypothalamic tissues of rats with anger emotion,” Journal of Chinese Integrative Medicine, vol. 9, no. 8, pp. 871–877, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. F. R. Wang, L. Xue, and H. Y. Zhang, “Effects of xiangshao granule on mRNA and protein expression of mu opioid receptor in premenstrual syndrome gan-qi invasion rats,” Zhongguo Zhong Xi Yi Jie He Za Zhi, vol. 32, pp. 1275–1279, 2012. View at Google Scholar
  5. Z. Jing, X. Yang, K. M. Ismail, X. Chen, and T. Wu, “Chinese herbal medicine for premenstrual syndrome,” Cochrane Database of Systematic Reviews, no. 1, Article ID CD006414, 2009. View at Google Scholar · View at Scopus
  6. M. Kubera, E. Obuchowicz, L. Goehler, J. Brzeszcz, and M. Maes, “In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression,” Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 35, no. 3, pp. 744–759, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. J. Li, Y. Zhou, B. B. Liu et al., “Nobiletin ameliorates the deficits in hippocampal BDNF, TrkB, and synapsin I induced by chronic unpredictable mild stress,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 359682, 11 pages, 2013. View at Publisher · View at Google Scholar
  8. M. Gazal, L. S. Motta, C. D. Wiener et al., “Brain-derived neurotrophic factor in post-partum depressive mothers,” Neurochemical Research, vol. 37, no. 3, pp. 583–587, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Benelli, M. Filaferro, A. Bertolini, and S. Genedani, “Influence of S-adenosyl-L-methionine on chronic mild stress-induced anhedonia in castrated rats,” British Journal of Pharmacology, vol. 127, no. 3, pp. 645–654, 1999. View at Publisher · View at Google Scholar · View at Scopus
  10. R. J. Katz, K. A. Roth, and B. J. Carroll, “Acute and chronic stress effects on open field activity in the rat: implications for a model of depression,” Neuroscience and Biobehavioral Reviews, vol. 5, no. 2, pp. 247–251, 1981. View at Publisher · View at Google Scholar · View at Scopus
  11. L. Chen, M. Chen, F. Wang et al., “Antidepressant-like effects of shuyusan in rats exposed to chronic stress: effects on hypothalamic-pituitary-adrenal function,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 940846, 9 pages, 2012. View at Publisher · View at Google Scholar
  12. J. Y. Guo, C. Y. Li, Y. P. Ruan et al., “Chronic treatment with celecoxib reverses chronic unpredictable stress-induced depressive-like behavior via reducing cyclooxygenase-2 expression in rat brain,” European Journal of Pharmacology, vol. 612, no. 1–3, pp. 54–60, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. L. Prut and C. Belzung, “The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review,” European Journal of Pharmacology, vol. 463, no. 1–3, pp. 3–33, 2003. View at Publisher · View at Google Scholar · View at Scopus
  14. R. P. Liu, J. L. Fang, P. J. Rong et al., “Effects of electroacupuncture at auricular concha region on the depressive status of unpredictable chronic mild stress rat models,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 789674, 7 pages, 2013. View at Publisher · View at Google Scholar
  15. R. S. Duman, “Neurotrophic factors and regulation of mood: role of exercise, diet and metabolism,” Neurobiology of Aging, vol. 26, supplement 1, pp. S88–S93, 2005. View at Publisher · View at Google Scholar · View at Scopus
  16. N. Hepgul, A. Cattaneo, P. A. Zunszain, and C. M. Pariante, “Depression pathogenesis and treatment: what can we learn from blood mRNA expression?” BMC Medicine, vol. 11, p. 28, 2013. View at Publisher · View at Google Scholar
  17. A. L. Lee, W. O. Ogle, and R. M. Sapolsky, “Stress and depression: possible links to neuron death in the hippocampus,” Bipolar Disorders, vol. 4, no. 2, pp. 117–128, 2002. View at Publisher · View at Google Scholar · View at Scopus
  18. D. Paredes, A.-C. Granholm, and P. C. Bickford, “Effects of NGF and BDNF on baseline glutamate and dopamine release in the hippocampal formation of the adult rat,” Brain Research, vol. 1141, no. 1, pp. 56–64, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Nibuya, S. Morinobu, and R. S. Duman, “Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments,” Journal of Neuroscience, vol. 15, no. 11, pp. 7539–7547, 1995. View at Google Scholar · View at Scopus
  20. T. Numakawa, S. Suzuki, E. Kumamaru, N. Adachi, M. Richards, and H. Kunugi, “BDNF function and intracellular signaling in neurons,” Histology and Histopathology, vol. 25, no. 2, pp. 237–258, 2010. View at Google Scholar · View at Scopus
  21. M. Gratacòs, J. R. González, J. M. Mercader, R. de Cid, M. Urretavizcaya, and X. Estivill, “Brain-derived neurotrophic factor Val66Met and psychiatric disorders: meta-analysis of case-control studies confirm association to substance-related disorders, eating disorders, and schizophrenia,” Biological Psychiatry, vol. 61, no. 7, pp. 911–922, 2007. View at Publisher · View at Google Scholar · View at Scopus
  22. Y. Ibarguen-Vargas, A. Surget, P. Vourc'h et al., “Deficit in BDNF does not increase vulnerability to stress but dampens antidepressant-like effects in the unpredictable chronic mild stress,” Behavioural Brain Research, vol. 202, no. 2, pp. 245–251, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. Y. Shirayama, A. C.-H. Chen, S. Nakagawa, D. S. Russell, and R. S. Duman, “Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression,” Journal of Neuroscience, vol. 22, no. 8, pp. 3251–3261, 2002. View at Google Scholar · View at Scopus