Antrodia camphorata Grown on Germinated Brown Rice Suppresses Melanoma Cell Proliferation by Inducing Apoptosis and Cell Differentiation and Tumor Growth

Figure 4

Effect of CBR EtOAc fraction on tumor growth in melanoma cell xenografted mice. (a) Average body weight of control and CBR, Dox-treated mice plotted over days after tumor cell inoculation: points: mean of seven animals. (b) Tumor nodule (arrow) and viscera mass (arrow head) of B16F10-inoculated mice treated with CBR (100 mg/kg/day) and Dox (1 mg/kg/day). (c) Tumor weight changes in B16F10-inoculated mice treated with CBR (100 mg/kg/day) and Dox (1 mg/kg/day) and controls (^∗𝑃<0.05, ^∗∗𝑃<0.01, ^∗∗∗𝑃<0.001).

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