Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Fig 1

Research Article

Molecular Mechanisms of Large-Conductance Ca2+-Activated Potassium Channel Activation by Ginseng Gintonin

Figure 1

The primary amino acid sequence of the mutated BKCa channel α subunit and the chemical structure of ginsenoside Rg3. (a) The brief sequence alignment of the BKCa channel and the mutated amino acid residues in the CaM kinase II phosphorylation sites (462, 512), PKA (939), PKC (1061), or Ca2+ binding sites of the Ca2+ bowl (989, 991, 992, 993, 994, 995) and RCK domains (433, 579). (b) The chemical structure of ginsenoside Rg3. Glc: glucose.

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