Review Article

Modified Dachengqi Decoction Combined with Conventional Treatment for Treating Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review Based on Randomized Controlled Trials

Table 1

Characteristics of included trials.

Study IDSample CM syndromeInterventionControlledCouseAdverse eventOutcome measures

Fang and Shi, 2006 [9]T: 20/18
C: 20/17
NSMDD Aminophylline 0.25 g qd, Methylprednisolone 80 mg q12h, Cefoperazone and Sulbactam 2 g q12h, Mucosolvan 75 mg q12h 5DNSBGA, DMV
Fu, 2010 [10]T: 30/30
C: 30/30
SPHOLMDDConventional treatment9DNSPF
Guo and Liang, 2011 [11]T: 60/60
C: 60/60
SPHOLMDDMucosolvan 60 mg and conventional treatment14DNSER
Guo and Zhang, 2008 [12]T: 30/30
C: 30/30
NSMDDConventional treatment7DNSPF, BGA, ER
Li, 2009 [13]T: 29/29
C: 27/27
SPHOLTongsai granule 6 g tidAminophylline 0.5 g, antibacterial15DNSInflammation factor
Li et al., 2003 [14]T: 60/60
C: 60/60
SPHOLMDDConventional treatment12DNSER
Li, 2006 [15]T: 30/30
C: 30/30
SPHOLMDDCefaclor capsules 0.25 g tid, Azithromycin tablets 0.5 g, Mucosolvan 30 mg tid.14DYSEPF, BGA, ER
Liang, 2011 [16]T: 30/30
C: 30/30
NSMDDConventional treatment15DNSPF, ER
Liu et al., 2002 [17]T: 25/25
C: 25/25
NSMDDConventional treatment12DNSOffline success rate
Lu, 2010 [18]T: 21/21 C: 21/21SPHOLMDDConventional treatment10DNSPF, BGA, ER
Mao, 2010 [19]T: 52/52
C: 48/48
NSTongfupaiqi mixtureConventional treatment14DYESPF
Meng, 2012 [20]T: 30/30
C: 30/30
SPHOLMDD Conventional treatment7DNSPF, ER
Pang, 2009 [21]T: 42/42
C: 40/40
SPHOLMDD Conventional treatment7DNSBGA
Peng and Li, 2009 [22]T: 30/30
C: 30/30
SPHOLMDDConventional treatment14DNSER
Shi et al., 2010 [23]T: 50/38
C: 30/20
NSMDD Conventional treatment28DNSDMV
Zhang, 2011 [24]T: 32/32
C: 30/30
SPHOLMDD Conventional treatment7DNSPF, ER

T: treatment; C: control; NS: not specified; conventional treatment: antibiotics, antispasmodic, expectorant (the drug is unknown); SPHOL: syndrome of phlegm-heat obstructing lung; BGA: blood gas analysis. PF: pulmonary function; ER: effective rate; DMV: duration of mechanical ventilation.