Activation of MITF by Argan Oil Leads to the Inhibition of the Tyrosinase and Dopachrome Tautomerase Expressions in B16 Murine Melanoma Cells
Figure 1
Effect of argan oil (AO) at 1/10000, 1/1000, and 1/100 (v/v) on the (a) melanin content (bar graph) and cell viability (line graph) of B16 melanoma cells cultured in 100 mm dish at a density of cells/dish. (b) Lysates of cells treated with or without arbutin (100 mM) or argan oil. B16 cells were treated with or without arbutin or argan oil serially diluted in Dulbecco’s Modified Eagles Medium and incubated for 48 or 72 h prior to melanin assay. *Statistically significant () difference between treated and untreated (Con) cells.
