Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients: A Four-Arm Randomized Trial on the Effectiveness of Electroacupuncture

Table 4

(a) CIPN perceived symptom severity (NRS) day 21–day 0 and day 84–day 0; (b) NRS—subjective CIPN complaints (ANCOVA day 21).

(a)  

Group	Day	Mean ± SD	Diff. mean; day 21–day 0; day 84–day 0
EA (𝑁=14)	0	4.0±1.7
	21	3.2±1.9	−0.8
	84	3.4±1.9	−0.6
HB (𝑁=13)	0	5.5±2.6
	21	3.8±2.9	−1.7
	84	4.7±3.3	−0.8
VitB (𝑁=15)	0	4.9±1.8
	21	3.3±2.3	−1.6
	84	3.1±1.6	−1.8
Placebo (𝑁=17)	0	4.9±2.1
	21	3.6±1.6	−1.3
	84	3.1±1.3	−1.8

(b)  

	Difference	95% CI	One-sided t-test	Two-sided t-test
EA versus placebo	0.3	−0.8–1.4	𝑃=0.705	𝑃=0.59
HB versus placebo	−0.2	−1.3–0.9	𝑃=0.35	𝑃=0.699
EA versus VitB	0.5	−0.6–1.7	𝑃=0.83	𝑃=0.34
HB versus VitB	0.0	−1.1–1.2	𝑃=0.52	𝑃=0.959
EA versus HB	0.2	−0.9–1.3	𝑃=0.65	𝑃=0.699
VitB versus placebo	−0.2	−1.3–0.8	𝑃=0.323	𝑃=0.646