Research Article

Antidiabetic Activity of Polysaccharides from Tuberous Root of Liriope spicata var. prolifera in KKAy Mice

Table 5

Effects of TLSP, LSP1, and LSP2 on hepatic glycogen content, G6Pase, and GK activities.

TreatmentHepatic glycogen content (mg/g)G6Pase activity (mU)GK activity (mU)

Diabetic control16.03 ± 0.120.71 ± 0.061.06 ± 0.08
Rosiglitazone10.64 ± 1.13**0.34 ± 0.07**3.08 ± 0.46**
Normal control18.30 ± 0.23**0.38 ± 0.03**3.55 ± 0.26**
TLSP 200 mg/kg17.46 ± 0.360.36 ± 0.05**3.44 ± 0.12**
TLSP 100 mg/kg18.26 ± 0.04**0.35 ± 0.02**3.24 ± 0.21**
LSP1 200 mg/kg18.11 ± 0.490.38 ± 0.02**3.49 ± 0.14**
LSP1 100 mg/kg18.92 ± 0.53**0.38 ± 0.03**3.36 ± 0.21**
LSP2 200 mg/kg17.66 ± 1.030.37 ± 0.06**3.36 ± 0.18**
LSP2 100 mg/kg16.55 ± 0.550.39 ± 0.02**3.31 ± 0.23**

Data were presented as mean ± SD ( ). ** versus diabetic control (vehicle-treated).