Prenylated Flavonoids from <i>Morus alba</i> L. Cause Inhibition of G1/S Transition in THP-1 Human Leukemia Cells and Prevent the Lipopolysaccharide-Induced Inflammatory Response

<table>Treatment with <i>M. alba </i>L. prenylated flavonoids causes accumulation of several cancer cells in G1 phase. (a) Cell cycle distribution at 24 h upon treatment of THP-1 cells with <b>1</b> as determined by flow cytometry. (b) Cell cycle distribution at 24 h upon treatment of THP-1 cells with <b>2</b> as determined by flow cytometry. (c) Cell cycle distribution at 24 h upon treatment of THP-1 cells with <b>3</b> as determined by flow cytometry. (d) Quantification of G1 subpeak in MA flavonoids treated THP-1 cells. (e) Cell cycle distribution at 24 h upon treatment of cancer PC3, DU-145, LAPC-4, and immortalized BPH-1 cells with <b>2</b> as determined by flow cytometry.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 2: Prenylated Flavonoids from <i>Morus alba</i> L. Cause Inhibition of G1/S Transition in THP-1 Human Leukemia Cells and Prevent the Lipopolysaccharide-Induced Inflammatory Response 

Figure 2 | Prenylated Flavonoids from Morus alba L. Cause Inhibition of G1/S Transition in THP-1 Human Leukemia Cells and Prevent the Lipopolysaccharide-Induced Inflammatory Response 