Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Tab 3

Review Article

Chinese Herbal Medicine for Osteoporosis: A Systematic Review of Randomized Controlled Trails

Table 3

Characteristics of clinical trials of Chinese herbs for osteoporosis.

Trial year prevention/treatment (reference)Number of patients
(treatment/control)
InterventionDurationOutcomes measured

Dai and Shen 2007 [10] 107 versus 85MGT 1.5 g/day XLGB 1.5 g/day versus placebo, all: (calcium 1000 mg/day)6 MBMD: lumber spine and femoral neck
Leung et al. 2011 [17]75 versus 75ELP 2.28 g/day versus placebo12 MBMD: lumber spine and femoral neck
Wu et al. 2009 [20]25 versus 25XLGB 1.5 g/day versus Calcitriol 0.25  g +
calcium 700 mg/day + vitamin D400 IU/day
6 MBMD: lumber spine and femoral neck
Zhang et al. 2005 [11]67 versus 66
versus 60
YGC 120 g/day versus Calcitriol 0.25  g versus placebo, all: (calcium 510 mg/day)6 MBMD: lumber spine and femoral neck
Ruan et al. 2006 [21]48 versus 42QGJN 0.75 g/day versus oral estradiol valerate 0.5–1.5 mg/day6 MBMD: lumber spine
Zhu et al. 2012 [12]109 versus 61XLGB 6 g/day versus placebo12 MBMD: lumber spine and femoral neck
Xiong et al. 2008 [13]73 versus 35JGKL 10 g/day versus placebo, all: (calcium 510 mg/day)6 MBMD: lumber spine and femoral neck
Zhou et al. 2009 [14]355 versus 119MGT 1.5 g/day versus XLGB 1.5 g/day6 MBMD: lumber spine and femoral
Liao et al. 2004 [15]32 versus 34BSSS soup 200 mL/day versus oral conjugated estrogen 0.5 mg/d and medroxyprogesterone 2.5 mg/d6 MBMD: lumber spine and femoral
Yang et al. 2007 [16]120 versus 120XLGB 1.5 g/day versus GKKFY 20 mL/day6 MBMD: lumber spine and femoral neck
Wang et al. 2006 [18]105 versus 105GSKC 2.56 g/day versus GSKT 20 g/day6 MBMD: femoral neck
Zheng et al. 2007 [19]55 versus 54JWGT 3 g/day versus placebo, all: (calcium 510 mg/day)6 MBMD: lumber spine and hip

MGT: Migu tablet; XLGB: Xian ling Gubao capsule; ELP: Bo-gu Ling capsules; YGC: Yigu capsule; QGJN: Qiang-Gu capsule; JGKL: Jiangu granule; BSSS: Bu Shen Sheng Sui soup; GKKFY: Gu Kang Oral liquid; GSKC: Gushukang capsule; GSKT: Gushukang granules; JWGT: Jinwugutong capsule; BMD: bone mineral density.

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