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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 356737, 12 pages
http://dx.doi.org/10.1155/2013/356737
Research Article

Positive Effect of Propolis on Free Radicals in Burn Wounds

1Department of Community Pharmacy, Medical University of Silesia in Katowice, 41-200 Sosnowiec, Poland
2Department of Biophysics, Medical University of Silesia in Katowice, 41-200 Sosnowiec, Poland
3Department of Clinical Chemistry and Laboratory Diagnostics, Medical University of Silesia in Katowice, 41-200 Sosnowiec, Poland
4Center of Experimental Medicine, Medical University of Silesia in Katowice, 40-752 Katowice, Poland

Received 4 April 2013; Accepted 1 May 2013

Academic Editor: Ewelina Szliszka

Copyright © 2013 Pawel Olczyk et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Concentration and properties of free radicals in the burn wounds treated with propolis were examined by the use of electron paramagnetic resonance spectroscopy. Magnetic spin-spin interactions and complex free radicals structures in wound beds were studied. The results were compared to those obtained for silver sulphadiazine used as a standard pharmaceutical agent. The changes of free radicals in the matrix of injury with time of exposition on these substances were tested. The aim of this study was to check the hypothesis about the best influence of propolis on the burn wounds healing. It was confirmed that a relatively lower concentration of free radicals exists in the burn wounds treated with propolis. The homogeneously broadened spectra and a complex free radical system characterize the tested tissue samples. The fastening of spin-lattice relaxation processes in the matrix of injury after treatment with propolis and silver sulphadiazine was observed. Practical usefulness of electron paramagnetic resonance spectroscopy in alternative medicine was proved.