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Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 368658, 11 pages
http://dx.doi.org/10.1155/2013/368658
Research Article

Antiobesity Effects of an Edible Halophyte Nitraria retusa Forssk in 3T3-L1 Preadipocyte Differentiation and in C57B6J/L Mice Fed a High Fat Diet-Induced Obesity

1Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8572, Japan
2Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8572, Japan
3Alliance for Research on North Africa (ARENA), University of Tsukuba, Tsukuba, Ibaraki 305-8572, Japan
4Laboratoire des Plantes Extrêmophiles, Centre de Biotechnologie à la Technopole de BorjCédria (CBBC), BP 901, 2050 Hammam-Lif, Tunisia

Received 19 April 2013; Revised 22 October 2013; Accepted 12 November 2013

Academic Editor: Mohamad Fawzi Mahomoodally

Copyright © 2013 Feten Zar Kalai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. WHO, Traditional Medicune Strategy, WHO, Geneva, Switzerland, 2002.
  2. M. Patricia and A. Donohoue, Energy Metabolism and Obesity: Research and Clinical Applications, Springer, 2008.
  3. S. Dave, N. J. Kaur, R. Nanduri, H. K. Dkhar, A. Kumar, and P. Gupta, “Inhibition of adipogenesis and induction of apoptosis and lipolysis by stem bromelain in 3T3-L1 adipocytes,” PLoS ONE, vol. 7, no. 1, Article ID e30831, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Dridi and M. Taouis, “Adiponectin and energy homeostasis: consensus and controversy,” Journal of Nutritional Biochemistry, vol. 20, no. 11, pp. 831–839, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. H. Inadera, “The usefulness of circulating adipokine levels for the assessment of obesity-related health problems,” International Journal of Medical Sciences, vol. 5, no. 5, pp. 248–262, 2008. View at Google Scholar · View at Scopus
  6. G. van den Berghe, “The role of the liver in metabolic homeostasis: implications for inborn errors of metabolism,” Journal of Inherited Metabolic Disease, vol. 14, no. 4, pp. 407–420, 1991. View at Google Scholar · View at Scopus
  7. M. Radonjic, J. R. de Haan, M. J. van Erk et al., “Genome-wide mRNA expression analysis of hepatic adaptation to high-fat diets reveals switch from an inflammatory to steatotic transcriptional program,” PLoS ONE, vol. 4, no. 8, Article ID e6646, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. N. A. G. Sahib, N. Saari, A. Ismail, A. Khatib, F. Mahomoodally, and A. Abdul Hamid, “Plants’ metabolites as potential antiobesity agents,” The Scientific World Journal, vol. 2012, Article ID 436039, 8 pages, 2012. View at Publisher · View at Google Scholar
  9. Tomoyasu Kamiya, Mayu Sameshima-Kamiya, Rika Nagamine et al., “The crude extract from puerariae flower exerts anti-obesity and anti-fatty liver effects in high-fat diet-induced obese mice,” Evidence-Based Complementary Alternative Medicine, vol. 2012, Article ID 272710, 6 pages, 2012. View at Publisher · View at Google Scholar
  10. J. Lee, E. Jung, J. Lee et al., “Isorhamnetin represses adipogenesis in 3T3-L1 cells,” Obesity, vol. 17, no. 2, pp. 226–232, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. C.-L. Hsu and G.-C. Yen, “Phenolic compounds: evidence for inhibitory effects against obesity and their underlying molecular signaling mechanisms,” Molecular Nutrition and Food Research, vol. 52, no. 1, pp. 53–61, 2008. View at Publisher · View at Google Scholar · View at Scopus
  12. J. Ahn, H. Lee, S. Kim, J. Park, and T. Ha, “The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways,” Biochemical and Biophysical Research Communications, vol. 373, pp. 545–549, 2008. View at Google Scholar
  13. A. W. Harmon and J. B. Harp, “Differential effects of flavonoids on 3T3-L1 adipogenesis and lipolysis,” American Journal of Physiology—Cell Physiology, vol. 280, no. 4, pp. C807–C813, 2001. View at Google Scholar · View at Scopus
  14. R. Ksouri, W. Megdiche Ksouri, I. Jallali et al., “Medicinal halophytes: potent source of health promoting biomolecules with medical, nutraceutical and food applications,” Critical Reviews in Biotechnology, vol. 32, no. 4, pp. 289–326, 2012. View at Google Scholar
  15. R. Ksouri, H. Falleh, W. Megdiche et al., “Antioxidant and antimicrobial activities of the edible medicinal halophyte Tamarix gallica L. and related polyphenolic constituents,” Food and Chemical Toxicology, vol. 47, no. 8, pp. 2083–2091, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. D. Ivanova, D. Gerova, T. Chervenkov, and T. Yankova, “Polyphenols and antioxidant capacity of Bulgarian medicinal plants,” Journal of Ethnopharmacology, vol. 96, no. 1-2, pp. 145–150, 2005. View at Publisher · View at Google Scholar · View at Scopus
  17. E. le Floc'h, Contribution a une etude Ethnobotanique de la Flore tunisienne, Ministere de l enseignement Superieure et de la Recherche Scientifique, 1952.
  18. A. El-Alali, A. AlZoubi, M. Gharaibeh, K. Tawaha, and F. Q. Alali, “Phytochemical and biological investigation of Nitraria retusa asch,” Jordan Journal of Pharmaceutical Sciences, vol. 5, no. 2, 2012. View at Google Scholar
  19. J. Boubaker, M. Ben Sghaier, S. Ines, K. Ghedira, and L. Chekir-Ghedira, “Isorhamnetin 3-O-robinobioside from Nitraria retusa leaves enhance antioxidant and antigenotoxic activity in human chronic myelogenous leukemia cell line K562,” BMC Complementary and Alternative Medicine, no. 12, p. 135, 2012. View at Google Scholar
  20. J. Boubaker, I. Skandrani, I. Bouhlel et al., “Mutagenic, antimutagenic and antioxidant potency of leaf extracts from Nitraria retusa,” Food and Chemical Toxicology, vol. 48, no. 8-9, pp. 2283–2290, 2010. View at Publisher · View at Google Scholar · View at Scopus
  21. J. Han and H. Isoda, “Capsaicin induced the upregulation of transcriptional and translational expression of glycolytic enzymes related to energy metabolism in human intestinal epithelial cells,” Journal of Agricultural and Food Chemistry, vol. 57, no. 23, pp. 11148–11153, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. J. Galgani and E. Ravussin, “Energy metabolism, fuel selection and body weight regulation,” International Journal of Obesity, vol. 32, no. 7, pp. S109–S119, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. J. Hadj Salem, I. Chevalot, C. Harscoat-Schiavo, C. Paris, M. Fick, and C. Humeau, “Biological activities of flavonoids from Nitraria retusa (Forssk.) Asch. and their acylated derivatives,” Food Chemistry, vol. 124, no. 2, pp. 486–494, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. S. R. Hussein, S. A. Kawashty, M. E. Tantawy, and N. A. M. Saleh, “Chemosystematic studies of Nitraria retusa and selected taxa of Zygophyllaceae in Egypt,” Plant Systematics and Evolution, vol. 277, no. 3-4, pp. 251–264, 2009. View at Publisher · View at Google Scholar · View at Scopus
  25. K. B. Pandey and S. I. Rizvi, “Plant polyphenols as dietary antioxidants in human health and disease,” Oxidative Medicine and Cellular Longevity, vol. 2, no. 5, pp. 270–278, 2009. View at Publisher · View at Google Scholar · View at Scopus
  26. C.-L. Hsu and G.-C. Yen, “Inhibitory effect of phenolic acids on the proliferation of 3T3-L1 preadipocytes in relation to their antioxidant activity,” Journal of Agricultural and Food Chemistry, vol. 54, no. 12, pp. 4191–4197, 2006. View at Publisher · View at Google Scholar · View at Scopus
  27. J.-Y. Yang, M. A. Della-Fera, S. Rayalam et al., “Enhanced inhibition of adipogenesis and induction of apoptosis in 3T3-L1 adipocytes with combinations of resveratrol and quercetin,” Life Sciences, vol. 82, no. 19-20, pp. 1032–1039, 2008. View at Publisher · View at Google Scholar · View at Scopus
  28. L. Aguirre, N. Arias, M. T. Macarulla, A. Gracia, and M. P. Portillo, “Beneficial effects of quercetin on obesity and diabetes,” The Open Nutraceuticals Journal, vol. 4, pp. 189–198, 2011. View at Publisher · View at Google Scholar · View at Scopus
  29. C. de Santi, A. Pietrabissa, F. Mosca, R. Spisni, and G. M. Pacifici, “Sulphation of resveratrol, a natural compound present in wine, and its inhibition by natural flavonoids,” Xenobiotica, vol. 30, no. 9, pp. 857–866, 2000. View at Google Scholar · View at Scopus
  30. Y.-C. Liang, S.-H. Tsai, L. Chen, S.-Y. Lin-Shiau, and J.-K. Lin, “Resveratrol-induced G2 arrest through the inhibition of CDK7 and p34CDC2 kinases in colon carcinoma HT29 cells,” Biochemical Pharmacology, vol. 65, no. 7, pp. 1053–1060, 2003. View at Publisher · View at Google Scholar · View at Scopus
  31. U. G. B. Haider, D. Sorescu, K. K. Griendling, A. M. Vollmar, and V. M. Dirsch, “Resveratrol increases serine15-phosphorylated but transcriptionally impaired p53 and induces a reversible DNA replication block in serum-activated vascular smooth muscle cells,” Molecular Pharmacology, vol. 63, no. 4, pp. 925–932, 2003. View at Publisher · View at Google Scholar · View at Scopus
  32. H. J. Park, J.-Y. Yang, S. Ambati et al., “Combined effects of genistein, quercetin, and resveratrol in human and 3T3-L1 adipocytes,” Journal of Medicinal Food, vol. 11, no. 4, pp. 773–783, 2008. View at Publisher · View at Google Scholar · View at Scopus
  33. H. Matsuda, Y. Kogami, S. Nakamura, T. Sugiyama, T. Ueno, and M. Yoshikawa, “Structural requirements of flavonoids for the adipogenesis of 3T3-L1 cells,” Bioorganic and Medicinal Chemistry, vol. 19, no. 9, pp. 2835–2841, 2011. View at Publisher · View at Google Scholar · View at Scopus
  34. X. Lin, G. Schonfeld, P. Yue, and Z. Chen, “Hepatic fatty acid synthesis is suppressed in mice with fatty livers due to targeted apolipoprotein B38.9 Mutation,” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 22, no. 3, pp. 476–482, 2002. View at Publisher · View at Google Scholar · View at Scopus
  35. A. Tirosh, I. Shai, R. Bitzur et al., “Changes in triglyceride levels over time and risk of type 2 diabetes in young men,” Diabetes Care Journal, vol. 31, no. 10, pp. 2032–2037, 2008. View at Publisher · View at Google Scholar · View at Scopus
  36. E. E. Mulvihill, E. M. Allister, B. G. Sutherland et al., “Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance,” Diabetes Journal, vol. 58, no. 10, pp. 2198–2210, 2009. View at Publisher · View at Google Scholar · View at Scopus
  37. G. R. Hajer, T. W. van Haeften, and F. L. J. Visseren, “Adipose tissue dysfunction in obesity, diabetes, and vascular diseases,” European Heart Journal, vol. 29, no. 24, pp. 2959–2971, 2008. View at Publisher · View at Google Scholar · View at Scopus
  38. J. M. Maglich, D. C. Lobe, and J. T. Moore, “The nuclear receptor CAR (NR1I3) regulates serum triglyceride levels under conditions of metabolic stress,” Journal of Lipid Research, vol. 50, no. 3, pp. 439–445, 2009. View at Publisher · View at Google Scholar · View at Scopus
  39. S. J. Wakil and L. A. Abu-Elheiga, “Fatty acid metabolism: target for metabolic syndrome,” Journal of Lipid Research, vol. 50, pp. S138–S143, 2009. View at Publisher · View at Google Scholar · View at Scopus
  40. K. Yamamoto, H. Shimano, M. Shimada et al., “Overexpression of apolipoprotein E prevents development of diabetic hyperlipidemia in transgenic mice,” Diabetes, vol. 44, no. 5, pp. 580–585, 1995. View at Google Scholar · View at Scopus
  41. H. Wang and R. H. Eckel, “Lipoprotein lipase: from gene to obesity,” American Journal of Physiology—Endocrinology and Metabolism, vol. 297, no. 2, pp. E271–E288, 2009. View at Publisher · View at Google Scholar · View at Scopus
  42. J. Lee, J. Lee, E. Jung, W. Hwang, Y.-S. Kim, and D. Park, “Isorhamnetin-induced anti-adipogenesis is mediated by stabilization of β-catenin protein,” Life Sciences, vol. 86, no. 11-12, pp. 416–423, 2010. View at Publisher · View at Google Scholar · View at Scopus
  43. H. Yoshida, N. Takamura, T. Shuto et al., “The citrus flavonoids hesperetin and naringenin block the lipolytic actions of TNF-α in mouse adipocytes,” Biochemical and Biophysical Research Communications, vol. 394, no. 3, pp. 728–732, 2010. View at Publisher · View at Google Scholar · View at Scopus
  44. J. Ahn, H. Lee, S. Kim, J. Park, and T. Ha, “The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways,” Biochemical and Biophysical Research Communications, vol. 373, no. 4, pp. 545–549, 2008. View at Publisher · View at Google Scholar · View at Scopus