Research Article

[Retracted] The Effect of Elephantopus scaber L. on Liver Regeneration after Partial Hepatectomy

Figure 5

Elephantopus scaber L. suppressed apoptosis during liver regeneration. (a) Expression protein levels of Bad and cytochrome c were decreased protein expression in Elephantopus scaber L. (ESL) and Silymarin (Sm) after 24 hrs and 72 hrs PHx by western blot. However, antiapoptosis protein, Bcl 2, was increased by Elephantopus scaber L. (ESL) and Silymarin (Sm) at after 24 hrs PHx, but no changes at 72 hrs PHx. (b) mRNA expression levels of Bad and cytochrome c decreased apoptosis in ESL and Sm treatment at 24 hrs PHx; however, we can observed a little elevated expression at 72 hrs PHx. In contrast, antiapoptosis protein, Bcl 2, was increased by Elephantopus scaber L. (ESL) and Silymarin (Sm) at 24 hrs, but no changes at 72 hrs. (c) TUNEL assay after traditional Chinese medicines in liver regeneration at 24 hrs and 72 hrs PHx. Only ESL and Sm have suppressed apoptosis function.
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