Research Article

Protective Effect of Qiliqiangxin Capsule on Energy Metabolism and Myocardial Mitochondria in Pressure Overload Heart Failure Rats

Table 3

The p-AMPK, AMPK, PGC-1α, CPT-I, and GLUT 4 protein expressions in myocardial tissue of different groups.

Groupp-AMPKAMPKPGC-1 CPT-IGLUT 4

Sham0.50 ± 0.120.67 ± 0.150.80 ± 0.121.15 ± 0.200.70 ± 0.14
Model0.31 ± 0.140.45 ± 0.170.29 ± 0.07##0.57 ± 0.10#0.39 ± 0.18#
Captopril0.79 ± 0.22**0.57 ± 0.360.76 ± 0.09**1.03 ± 0.32*0.71 ± 0.27*
QL-L0.68 ± 0.24*0.49 ± 0.160.35 ± 0.030.65 ± 0.170.62 ± 0.02
QL-M0.79 ± 0.11**0.44 ± 0.140.53 ± 0.06**0.93 ± 0.270.75 ± 0.15*
QL-H0.94 ± 0.13**0.63 ± 0.220.75 ± 0.03**1.07 ± 0.36*0.81 ± 0.14**

Sham: control group; TAC: model group; QL-L: low-dose QL group; QL-M: medium-dose QL group; QL-H: high-dose QL group; values were expressed as mean ± standard deviation. Compared with TAC, P < 0.05, P < 0.01; compared with TAC, P < 0.05, P < 0.01.