Evidence-Based Complementary and Alternative Medicine / 2013 / Article / Fig 3

Research Article

The Methanol Extract of Angelica sinensis Induces Cell Apoptosis and Suppresses Tumor Growth in Human Malignant Brain Tumors

Figure 3

AS-M suppressed tumor growth and prolonged the animal survival rate in mice subcutaneously implanted with human GBM cells. DBTRG-05MG cells were implanted s.c. into the hind flank region of Foxn1 nu/nu mice. The mice were treated with vehicle as a control or AS-M (500 mg/kg/day) at days 3, 6, and 9. (a) AS-M inhibited the tumor growth and (b) prolonged the survival rate in these mice. The mice were sacrificed when the tumor size exceeded 1000 mm3. The tumor size values are means ± SE.

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