Protective Effects of Fufang Xueshuantong on Diabetic Retinopathy in Rats

<table>Effects of FXT on the expression of occludin and ICAM-1 of retina in STZ rats. Diabetic rats received a single dose of 60 mg/kkg STZ by i.p. Control rats received vehicle. After one week, STZ rats with blood glucose levels greater than 16.7 mmol/L were assigned into STZ group, FXT 0.525 g/kg group, and FXT 1.05 g/kg group. FXT-diabetic rats received FXT 0.525 g/kg or FXT 1.05 g/kg by ig once daily for consecutively 24 weeks. Occludin and ICAM-1 in retina were detected with western blot. The expression of occludin (a) and ICAM-1 (b) was quantified using densitometry and normalized by <i>β</i>-actin. Values are demonstrated as mean ± SD; <svg height="11.125" id="M76" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.125" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus control rats; <sup>#</sup><svg height="11.375" id="M78" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus STZ rats.</table>

Evidence-Based Complementary and Alternative Medicine

fig5

Figure 5

Figure 5: Protective Effects of Fufang Xueshuantong on Diabetic Retinopathy in Rats 