Research Article

Protective Effects of Fufang Xueshuantong on Diabetic Retinopathy in Rats

Figure 6

Effects of FXT on the expression of VEGF and PEDF of retina in STZ rats. Diabetic rats received a single dose of 60 mg/kg STZ by i.p. Control rats received vehicle. After one week, STZ rats with blood glucose levels greater than 16.7 mmol/L were assigned into STZ group, FXT 0.525 g/kg group, and FXT 1.05 g/kg group. FXT-diabetic rats received FXT 0.525 g/kg or FXT 1.05 g/kg by ig once daily for consecutively 24 weeks. Typical immunohistochemistry staining for VEGF and PEDF in retina was shown in panel (a). The optical density of VEGF and PEDF was quantified using the Image Pro Plus Analysis Software as shown in panels (b) and (c). . * versus control rats; # versus STZ rats.
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(a)
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(b)
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(c)