Subacute and Reproductive Oral Toxicity Assessment of the Hydroethanolic Extract of Jacaranda decurrens Roots in Adult Male Rats

Table 1

Body weight and relative organs weights of animals exposed to Jacaranda decurrens in the subacute toxicity study.

Parameter	Control (vehicle)	250 mg/kg	500 mg/kg	1000 mg/kg
Body weight (g)	430.00±22.31	422.00±22.10	439.00±32.21	426.00±18.20
Liver (g/100 g)	2.78±0.07	2.74±0.06	2.67±0.21	2.70±0.10
Lung (g/100 g)	0.43±0.16	0.49±0.03	0.44±0.02	0.42±0.02
Kidney (g/100 g)	0.31±0.01	0.32±0.01	0.30±0.01	0.29±0.01
Testis (g/100 g)	0.49±0.02	0.47±0.01	0.44±0.01	0.43±0.01
Epididymis (mg/100 g)	147.00±0.01	167.00±0.01	157.00±0.01	158.00±0.01
Prostate (mg/100 g)	124.00±0.02	155.00±0.02^∗	166.00±0.01^∗	122.00±0.01
Vas deferens (g/100 g)	0.04±0.00	0.08±0.04	0.14±0.09	0.03±0.00
Seminal vesicle (g/100 g)	0.43±0.02	0.40±0.02	0.37±0.01	0.40±0.01

Values expressed as mean ± SEM, 𝑛=8 animals/group. ^∗𝑃<0.05 by ANOVA-Tukey Kramer test compared with control group.